To reduce the development of drug-resistant bacteria and maintain the effectiveness of AVEROBIOS and other antibacterial drugs, AVEROBIOS should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
AVEROBIOS should be taken at the start of a meal to enhance the absorption of amoxicillin and to minimize the potential for gastrointestinal intolerance. Absorption of the amoxicillin component is decreased when AVEROBIOS is taken on an empty stomach .
Pediatric patients who weigh 40 kg or more and can swallow tablets should receive the adult dose.
The recommended dose of AVEROBIOS XR is 4,000 mg/250 mg daily according to the following table:
|Acute bacterial sinusitis||2 tablets q12h||10 days|
|Community-acquired pneumonia||2 tablets q12h||7-10 days|