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Ronisirox

Blood Treatment
Product

Ronisirox Tablet for oral suspension

Active

Deferasirox 500 mg

Category
Blood Treatment
Indication

Ronisirox is indicated for the treatment of chronic iron overload due to frequent blood transfusions (≥7 ml/kg/month of packed red blood cells) in patients with beta thalassaemia major aged 6 years and older.

Ronisirox is also indicated for the treatment of chronic iron overload due to blood transfusions when deferoxamine therapy is contraindicated or inadequate in the following patient groups:

In patients with beta thalassaemia major with iron overload due to frequent blood transfusions (≥7 ml/kg/month of packed red blood cells) aged 2 to 5 years.

In patients with beta thalassaemia major with iron overload due to infrequent blood transfusions (<7 ml/kg/month of packed red blood cells) aged 2 years and older.

In patients with other anaemias aged 2 years and older.

Ronisirox is also indicated for the treatment of chronic iron overload requiring chelation therapy when deferoxamine therapy is contraindicated or inadequate in patients with non-transfusion-dependent thalassaemia syndromes aged 10 years and older.

Dose

You must take the medicine as prescribed by the doctor.

How much Ronisirox to take:

  • The dose of Ronisirox is determined based on your body weight, which the doctor will calculate for you.
  • The usual daily dose of it at the start of treatment is 20 mg per kg. For patients who receive regular blood transfusions, the dose may be increased or decreased depending on the patient’s health condition or circumstances.
  • The usual daily dose for patients who do not have regular blood transfusions is 10 mg per kg.
  • Your doctor may change your dose depending on how you respond to treatment.

The maximum daily dose is 40 mg per kg for patients who receive regular blood transfusions, 20 mg per kg for patients who do not have regular blood transfusions, 10 mg per kg for children who are not regularly transfused.